Extended adjuvant treatment of early breast cancer: Flushing, asthenia, edema, arthralgia, myalgia, back pain, headache, dizziness, increased sweating, constipation, nausea, diarrhea, hypercholesterolemia, vag hemorrhage, vulvovag dryness, insomnia, dyspnea, infections & infestations & renal disorders. 1st-line breast cancer: Bone/back pain, hot flushes, nausea, arthralgia, dyspnea. Fatigue, chest pain, decreased wt, pain, weakness, hot flushes, lower limb edema, HTN, constipation, diarrhea, vomiting, decreased appetite, abdominal pain, flu, limb pain, headache, insomnia, breast pain, coughing, alopecia/hair thinning, post-mastectomy lymphoedema. 2nd-line breast cancer: Fatigue, chest pain, peripheral edema, asthenia, increased wt, HTN, nausea, vomiting, constipation, diarrhea, abdominal pain, anorexia, dyspepsia, viral infection, hypercholesterolemia, somnolence, dizziness, dyspnea, coughing, hot flushes, rash, pruritus.